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Administration of Medicinal Cannabis

Medicinal Cannabis is delivered to the bloodstream using inhalation, oral and topical methods of administration. In New Jersey, forms of administration include vaporizers and smoking, edible products such as lozenges, sublingual formulations, creams and lotions.

Inhalation is the fastest-acting method of administration other than intravenous injection. When inhaled, the active ingredients of Cannabis pass directly into the bloodstream from the lungs. Peak blood levels are achieved within 5-20 minutes and the pharmacological activity is typically within 3 hours. Examples are smoking, vaporizers and nebulizers.

Oral administration is a slower-acting method because the active ingredients of Cannabis must pass through the gastrointestinal tract during digestion before entering the bloodstream. Pharmacological effects occur in 30-90 minutes. Oral administration also alters the chemistry of therapeutical ingredients by “first pass” metabolism in the digestive tract. Examples are edibles and sublingual forms.

Topical forms are typically used as creams or lotions to treat localized pain and discomfort, delivering active ingredients to the bloodstream through the skin Examples are topical lotions.

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Inhalation
• Compassionate Sciences offers over 23 varieties and strains of flower “bud” containing a complete profile of cannabinoids included but not limited to THCA, CBDA, CBGA and other essential cannabinoids that provide patient experience.

Compassionate Sciences offers indica, sativa and hybrid strains that are recommended for the treatment of all qualifying medical conditions.

Patients find flower “bud” to be helpful with all conditions and side effects such as depression, stress, chronic pain, fatigue, anxiety and many more.

Lozenges-on-trayOral Administration
• Compassionate Sciences offers Lozenges containing Tetrahydrocannabinol and Cannabidiol, both of which have medicinal benefits.

These soft tablets are meant to dissolve slowly in the patient’s mouth and absorbed into the blood stream through the mucosal membrane.

Patients find lozenges to be helpful with pain relief, inflammation, muscles spasms, cramps, menstrual pain and migraines.

 

 

Product-Lozenge
Product Description:
Cannabis infused Lozenges

1/8 oz container
Contains 30 individual Lozenge troches
Total: 300mg THC
30mg CBD
Each troche is a single dose containing 10mg THC : 1mg CBD
Effects: Relaxing, Pain Relief
Conditions: Chronic Pain, Inflammation, Arthritis, Migraines, Muscle Spasms

 

Oil-webTopical Administration
• Compassionate Sciences offers a topical in the form of a pure-clean cannabis extract derived through supercritical extraction with CO2 as the active solvent. Compassionate Sciences also provides a Cocoa Butter based lotion. Both contain Tetrahydrocannabinol and Cannabidiol.

When administered properly these topical formulas do not produce psychotropic effects, but instead offer fast acting, long lasting, localized relief.

Topical cannabis products are helpful in relieving localized pain, inflammation, burns, both bacterial and fungal skin infections, itching and psoriasis, muscle spasms and cramps and migraines or headaches.

Topical products are also commonly used to improve skin elasticity, reduce acne, shrink skin abnormalities such as warts or skin tags and used as personal lubricants.

Product-Lotion
Product Description:
Cannabis infused Cocoa Butter Lotion

1/8 oz container
Total: 300mg THC
30mg CBD
30 doses / container
Each (1mL or 1g ) dose = 10mg THC:1mg CBD
Ingredients: Extract, Coconut Oil, Cocoa Butter
Effects: Relaxing, Pain Relief
Conditions: Chronic Pain, Inflammation, Arthritis, Migraines, Muscle Spasms
Product-Topical
Product Description:
Cannabis Topical Oil

1/8 oz container
Contains one syringe with 0.6g of medicine
Total: 300mg THC
30mg CBD
30 doses / syringe
Each dose = 2 marked graduated units on syringe (10mg THC:1mg CBD)
Ingredients: Extract and Up to 5% VG if applicable
Effects: Relaxing, Pain Relief
Conditions: Chronic Pain, Inflammation, Arthritis, Migraines, Muscle Spasms

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New Jersey’s medical marijuana industry posted a banner year in 2016

pngNew Jersey’s medical marijuana industry posted a banner year in 2016, with patient counts ballooning 76% and sales volume doubling thanks to a series of small changes to the state’s MMJ program and the opening of two new dispensaries.

This is welcome news for a program that has struggled to enroll patients amid high MMJ prices, weak doctor participation and limited access to treatment centers.

Over the course of 2016, New Jersey added roughly 4,600 patients to the MMJ program, ending the year at nearly 11,000. Sales of MMJ jumped by an even greater degree, as the state’s five dispensaries sold a combined 2,694 pounds of cannabis in 2016, a 119% increase from the previous year.

Two of those five dispensaries – Breakwater Alternative Treatment Center in Cranbury and Compassionate Sciences Alternative Treatment Center in Bellmawr– came online in late 2015. The addition of these dispensaries is responsible for much of the growth in sales but is likely driving patient counts as well.

Compassionate Sciences, for example, opened in September 2015 in western New Jersey, just outside of Philadelphia. The dispensary is located in an area of the state not covered by the other four dispensaries, and it ended 2016 with significantly more MMJ sales than all its competitors.

Foundation Harmony, the sixth and final dispensary to be awarded a license, is still undergoing examination from the state before being allowed to open.

These two new dispensaries also added some much-needed competition to the market, lowering MMJ prices in the state to about $300 per ounce, down from highs of nearly $500 per ounce.

New Jersey prices were previously some of the highest of any MMJ market in the nation and likely prevented many would-be patients from seeking an MMJ recommendation. State data shows that 45% of registered patients qualified for and received a reduced application fee. The discount is given to patients who receive some form of government assistance, including – but not limited to – Medicaid and disability benefits.

Beyond the addition of new dispensaries, the state has also made changes to the MMJ program that should further boost patient counts.

Despite his misgivings, Republican Gov. Chris Christie signed legislation adding PTSD to the list of qualifying MMJ conditions last September. By the end of the year, nearly 500 patients with PTSD qualified for the program, accounting for approximately 4% of all MMJ patients in the state.

In July, New Jersey’s health department instituted a program that allows the public to petition to have ailments added to the list of qualifying MMJ conditions. According to the Department of Health, 45 conditions met the program’s guidelines and were passed on to the Medicinal Medical Review Panel. The panel will hold meetings throughout 2017 to consider those petitions.

The program still faces challenges, however, as industry observers believe it still needs more licensed physicians willing to recommend marijuana, while restrictions on the types of MMJ products allowed to be sold may lead potential patients to the black market.

 

 

Source
New Jersey Department of Health

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March is Multiple Sclerosis Awareness Month

ms-robbon-blue-orangeIn light of Multiple Sclerosis Awareness Month, we want raise awareness about the scientific evidence showing cannabis as a palliative treatment for Multiple Sclerosis.

Multiple Sclerosis [MS], as we know it, is an autoimmune disease that results in the slowing of the speed of signals sent from the central nervous system to the peripheral nervous system and can even result in irreversible damage to the nerves in the central nervous system that were once protected by the myelin sheath. This condition can leave a patient suffering from a wide range of symptoms including fatigue, depression, weakness, spasms, spasticity, pain, sleep disturbances and more.

One of the largest studies on the effect of medical cannabis on patients with MS stated that patients who used Tetrahydrocannabinol reported improvements in pain, sleep quality, spasms and spasticity.

There is even evidence that suggests that cannabinoids may have immunomodulatory effects, and have therapeutic benefits in treating MS. 1

Current studies show that patients who perceive initial benefits from their cannabis medication experienced persisting positive effects into extended trials without tolerance.[1]

Of a small group of MS patients who participated in an abrupt interruption of their cannabis medication, there was no consistent withdrawal symptoms and five patients had to resume taking their medication due to reemergence of symptoms.

Symptomatic medications often do not provide adequate relief and may have toxic effects that can worsen a patient’s already diminished quality of life.1 These effects can be weighed in comparison to cannabis’s relatively limited side effects.

For more information on research studies relating to cannabis click here.

 

[1] Hazekamp, Arno, and Franjo Grotenhermen. “Review on Clinical Studies with Cannabis and Cannabinoids 2005-2009.” 5.Special Issue (2010): 1-21. Print.

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Introduction to Terpenes


TerpenesThe cannabis plant consists of a wide variety of chemicals and compounds. About 140 of these belong to a large class of aromatic organic hydrocarbons known as terpenes (pronounced tur-peens). You may have also heard people talk about terpenoids. The words terpene and terpenoid are increasingly used interchangeably, although these terms do have different meanings. The main difference between terpenes and terpenoids is that terpenes are hydrocarbons (meaning the only elements present are carbon and hydrogen); whereas, terpenoids have been denatured by oxidation (drying and curing the flowers) or chemically modified.

Terpenes are synthesized in cannabis in secretory cells inside glandular trichomes, and production is increased with light exposure. These terpenes are mostly found in high concentrations in unfertilized female cannabis flowers prior to senescence (the condition or process of deterioration with age). The essential oil is extracted from the plant material by steam distillation or vaporization. Many terpenes vaporize around the same temperature as THC (which boils at about 157°C), but some terpenes are more volatile than others. Terpenes also play an incredibly important role by providing the plant with natural protection from bacteria and fungus, insects and other environmental stresses.

It is well established that cannabis is capable of affecting the mind, emotions and behavior. The main psychotropic cannabinoid, delta-9-tetrahydrocannabinol (THC) has been intensely studied. However, many of the other cannabinoids, terpenoids and flavonoids found in medical marijuana that play a big role in boosting the therapeutic effect of cannabis remain understudied.

Terpenes are common constituents of flavorings and fragrances. Terpenes, unlike cannabinoids, are responsible for the aroma of cannabis. The FDA and other agencies have generally recognized terpenes as “safe.” Terpenes act on receptors and neurotransmitters; they are prone to combine with or dissolve in lipids or fats; they act as serotonin uptake inhibitors (similar to antidepressants like Prozac); they enhance norepinephrine activity (similar to tricyclic antidepressants like Elavil); they increase dopamine activity; and they augment GABA (the “downer” neurotransmitter that counters glutamate, the “upper”). However, more specific research is needed for improved accuracy in describing and predicting how terpenes in cannabis can be used medicinally to help treat specific ailments / health conditions.

 

Want to learn more about Terpenes and how they assist in the medical benefits of Cannabis? Click to learn more

 

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Patient Recipe: Caramel Chews


Caramel Chews
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Ingredients:
1 cup cannabutter
1 lb light brown sugar
1 (14 oz) can of sweetened condensed milk
1 cup light corn syrup
1 pinch of salt
1 1/2 tsp of vanilla

Directions:


1. In a heavy bottomed saucepan over medium heat, combine the cannabutter, brown sugar, sweetened condensed milk, corn syrup and salt. Bring to a boil, stirring constantly. Heat to between 234 and 240 degrees F (112 to 116 degrees C), or until a small amount of syrup dropped into cold water forms a soft ball that flattens when removed from the water and placed on a flat surface. Cook for 2 minutes at that temperature. Remove from the heat and stir in vanilla.

2. Meanwhile, butter a 9×13 inch baking pan. When the caramel is ready, pour into the buttered pan. Allow to cool completely at room temperature. Remove from the pan and cut into squares using scissors. Wrap individual pieces in waxed paper or cellophane.

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Welcome

Welcome to Compassionate Sciences Alternative Treatment Center News. Our goal is to keep you informed about Cannabis-based therapies and how they can mitigate disease symptoms and offer a natural alternative to powerful pharmaceutical drugs that have debilitating side-effects. You may also signup to receive our RSS feed and get email alerts about our progress and to subscribe to our eNewsletter to stay connected to our news and updates.

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